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Read more about our offers and requirements. In an interdisciplinary research approach we address the effects of hormones derived from adipose tissue adipokines on CNS function and, in turn, the control of adipose tissue and body weight by the brain.

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Adipocytes secrete bioactive factors that act in an autocrine, paracrine, or endocrine manner similar to the cytokine peptides of the immune system, thus termed adipokines. Since the Lady b Lubeck of the first adipokine, leptin, a growing number of such fat cell-derived peptide hormones has been described including adiponectin, nesfatin-1, or visfatin; but also inflammatory cytokines and steroid hormones.

Adipokines signal the adipose state to appetite-regulating centres of the brain. In the hypothalamusleptin inhibits appetite-promoting neurons in the arcuate nucleus and promotes energy expenditure via stimulation of sympathetic nerve Singles Bad Salzuflen ltd to adipose tissues.


Such feedback mechanisms also exist for other adipokines. The complex autoregulatory feedback system between central and adipose tissues is essentially involved in adjusting setpoints of energy homeostasis. Organization People Jobs.

Projects International Partners Publications. During my lab stay I will investigate circadian rhythms of white adipose tissue, wrist temperature, and activity as predictors for weight-loss efficiency by bariatric surgery.

German States before F-M

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To Kleve date understand the similarities and Lqdy differences of Lubecck complex immunological networks underlying allergic and infection-associated inflammation, systems immunology approaches will be implemented that have been developed by our partner university in Cincinnati.

With this program the IRTG aims at identifying novel target molecules or signaling pathways in order to come up with innovative therapeutic strategies and at educating immunologists for the domestic and international job Lady b Lubeck at the interface between allergy and infectious disease research. The research program is supplemented by a structured qualification and cross-border supervisory concept Luheck defined training modules that integrates student exchanges between the German and the US partner institutions.

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